心率/体温比:对于患有败血症的重症患者来说,这是一个实际的预后指标
1Emergency and Critical Care Center, Intensive Care Unit, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China.
Heliyon
|January 31, 2024
概括
心率/温度比可以预测毒症患者的重症监护室 (ICU) 死亡率. 较高的比率,特别是超过2.22,与增加的ICU死亡风险密切相关.
科学领域:
- 临界护理医学 临界护理医学
- 临床生理学 临床生理学
背景情况:
- 败血症是一种危及生命的疾病,需要准确的预后指标.
- 目前用于预测败血症患者死亡率的方法可能很复杂.
- 一个简单,易于获得的预测因素可以改善临床决策.
研究的目的:
- 为了研究心率/温度比率与重症监护室 (ICU) 死亡率在重症败血症患者之间的关联.
- 确定心率/温度比是否可以作为ICU死亡率的独立预测指标.
主要方法:
- 利用了包括12,321名败血症患者在内的全面重症监护医学数据库.
- 采用多变量逻辑回归来评估心率/温度比对ICU死亡率的影响.
- 进行了子组分析和敏感性分析以证实发现.
主要成果:
- 发现心率/温度比和ICU死亡率之间存在非线性关系,转折点为2.22.
- 高心率/温度比 (>2.22) 独立地与55%更高的ICU死亡率 (OR=1.55) 相关.
- 作为连续变量,该比率与ICU死亡率 (OR=2.14) 有正相关性.
结论:
- 心率与体温的比率是一个方便且易于获得的临床指标.
- 心率/体温比升高,特别是超过2.22,与感染性败血症患者的ICU死亡率增加密切相关.
- 这一比率为危急性败血症患者的风险分层提供了有价值的工具.
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