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光可视化用于癌症检测:经验和前景

Yaroslav Kravchenko^1,2, Kateryna Sikora¹, Andrew Awuah Wireko¹

¹Sumy State University, Sumy, Ukraine.

|January 31, 2024

概括

近红外光成像帮助外科医生在手术期间可视化瘤和转移. 这种先进的技术提高了癌症检测和手术精度,但补充,而不是取代传统的诊断方法.

科学领域:

医疗成像医学成像
在瘤学瘤学.
手术技术手术技术

背景情况:

光成像,特别是近红外 (NIR) 光,正在推进癌症检测和手术指导.
目前的技术利用光剂和专用摄像机来增强瘤和周围组织的可视化.

研究的目的:

审查用于癌症应用的光成像技术的最新进展.
突出光引导手术 (FGS) 在改善手术结果和检测转移性病变方面的作用.

主要方法:

关于NIR光成像和FGS的当前文献的综述.
分析光可视化在癌症检测临床实践中的整合.
讨论针对性光成像探针的开发.

主要成果:

尼尔射线光成像与有针对性的追踪器和摄像头相结合,有效地可视化瘤,并有助于导航手术场所.
FGS协助外科医生区分解剖结构,评估组织输液,并在手术期间识别转移.
临床应用显示了光可视化的显著潜力,作为标准癌症诊断的辅助.

结论:

光成像是癌症手术中宝贵的辅助工具,可以提高可视化和精度.
它补充了,但不能取代已有的诊断方法,如活检和CT扫描.
未来的发展重点是高度选择性的光探针,用于精确向癌细胞和划分瘤边缘.

关键词:

癌症诊断癌症的诊断癌症的诊断光标签的使用方法光探测器的光探测器光结合抗体光结合抗体在手术内进行光诊断.

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Immunofluorescence Microscopy

Immunofluorescence Microscopy

A fluorescence microscope uses fluorescent chromophores called fluorochromes, which can absorb energy from a light source and then emit this energy as visible light. Fluorochromes include naturally fluorescent substances (such as chlorophylls) and fluorescent stains that are added to the specimen to create contrast. Dyes such as Texas red and FITC are examples of fluorochromes. Other examples include the nucleic acid dyes 4’,6’-diamidino-2-phenylindole (DAPI), and acridine orange.