在lncRNA GAS5上调节ANXA2以调节动脉样硬化发育期间的巨细胞炎症反应

Yuzhou Xue1,2, Yu Hu2,3, Shikai Yu4

  • 1Department of Cardiology and Institute of Vascular Medicine, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University Beijing Key Laboratory of Cardiovascular Receptors Research, Peking University Third Hospital, Beijing, China.

Heliyon
|January 31, 2024
PubMed
概括

这项研究表明,长非编码RNA GAS5 (增长停止特异性5) 和附件A2 (ANXA2) 通过增加巨细胞炎症和亡来促进动脉样硬化. 它们的相互作用调解了炎症反应,为动脉样硬化提供了潜在的治疗点.