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Updated: Jul 4, 2025

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在精神分裂症中,通过全外体序列进行基于家族的遗传分析,以识别罕见的致病变体

Binli Shang1, Runxu Yang1,2, Kun Lian1

  • 1Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, Kunming, China.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
|January 31, 2024
PubMed
概括

整体外基因组测序在两个家族的六个与精神分裂症 (SCZ) 相关的基因中发现了新的同卵性突变. 这些发现突显了遗传异质性,并扩大了对SCZ的理解.

关键词:
同卵性突变是同卵性突变.这是一种衰退式继承.精神分裂症 (SCZ) 是一种疾病.整体外体组序列化 (WES) 是一种全外体组序列化.

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