医生全球评估 国际标准化 系统性红斑狼中的共识:PISCOS研究
Matteo Piga1, Elisabetta Chessa1, Eric F Morand2
1Rheumatology Unit, AOU University Clinic and University of Cagliari, Cagliari, Italy.
The Lancet. Rheumatology
|January 31, 2024
概括
医生全球评估国际标准化共识在系统性红斑狼 (PISCOS) 研究标准化医生全球评估 (PGA) 系统性红斑狼 (SLE) 疾病活动. 这种共识提高了PGA在临床实践和试验中的可靠性.
科学领域:
- 类风湿病学 类风湿病学
- 临床免疫学临床免疫学
- 医学统计 医学统计
背景情况:
- 系统性红斑狼 (SLE) 需要准确的疾病活动评估.
- 医生全球评估 (PGA) 是至关重要的,但缺乏标准化的评分.
- 医生全球评估国际标准化共识在系统性红斑狼 (PISCOS) 研究解决了这一需求.
研究的目的:
- 建立基于证据和专家共识的标准,用于SLE的PGA.
- 为临床实践和研究开发可靠和均的PGA评分系统.
主要方法:
- 一个三轮的德尔菲共识过程,涉及79名国际SLE专家.
- 评分 41 个关于 SLE 的 PGA 陈述,使用 0-10 数值尺度.
- 共识定义为≥75%的同意,其次是验证.
主要成果:
- 在27项声明上达成共识,形成了14项建议.
- 推PGA的0-3视觉模拟尺度,评估前一个月的疾病活动.
- PGA包括活跃表现和实验室结果,不包括损伤和血清学;规模定义了轻度,中度和严重的活动.
结论:
- 皮斯科斯研究建立了针对SLE的标准化PGA建议.
- 这种标准化旨在提高PGA评级的均性和可靠性.
- 结果将有助于定义缓解,低疾病活性,并改善未来的SLE临床试验.
相关概念视频
Assessment of the Cardiovascular System III: Palpation
342
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
342
Assessment of the Cardiovascular System I: Subjective Data
343
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
343
Assessment of the Cardiovascular System II: Inspection
252
Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck
Head and Neck
252
Assessment of the Gastrointestinal System I: Subjective Data
198
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
198


