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[Platycodin D通过降低TRPC6表达和减少肺纤维细胞中的ROS产量来改善小鼠的肺纤维化]

Z Liang1, C Yu1, S Liang1

  • 1Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

Nan fang yi ke da xue xue bao = Journal of Southern Medical University
|January 31, 2024
PubMed
概括

普拉提科丁D (PD) 通过降低α-平滑肌动蛋白和TRPC6表达,有效地治疗小鼠的肺纤维化. 这种天然化合物通过抑制细胞增殖和减少活性氧物种 (ROS) 来缓解肺损伤.

关键词:
普拉提科丁 D D肺部纤维化 肺部纤维化有活性氧物种的反应性氧物种.短暂受体潜在阴离子通道亚家族C成员6

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