在新生儿重症监护室实施增强的亲肠营养方案后的身体组成:随机试验试验
Emily M Nagel1, Jennifer Super2, Nicholas A Marka3
1Division of Epidemiology and Community Health, School of Public Health, University of MN, Minneapolis, MN, USA.
Annals of human biology
|January 31, 2024
概括
在这项试点研究中,对出生时体重非常低 (VLBW) 婴儿的增强性腹腔营养并没有显著改变生长或身体组成. 需要进一步的研究,以在更大的试验中证实这些发现.
科学领域:
- 新生儿科学 新生儿科学
- 儿童营养学 儿童营养学
- 增长和发展 增长和发展
背景情况:
- 非常低出生体重 (VLBW) 婴儿面临生长衰竭和神经发育问题的风险.
- 优化管营养旨在改善生长,但引起了人们对早期脂肪和以后代谢疾病的担忧.
研究的目的:
- 研究VLBW早产婴儿中增强或标准肠道营养和生长/身体组成之间的关联.
- 评估早期营养方案对新生儿重症监护室结果的影响.
主要方法:
- 一项临床试验的二次分析,该试验涉及将VLBW婴儿随机分配到标准或增强的亲肠道营养.
- 混合效应线性回归模型用于评估出院前临床稳定的婴儿的每周生长和身体组成.
主要成果:
- 在增强型和标准门营养组之间,没有发现婴儿生长或身体组成的统计学上显著差异.
- 观察到的营养方案与生长/身体成分测量之间的关联在统计学上并不显著 (p >.05).
结论:
- 在这项试点试验中,在生命的第一个星期中增强的亲肠道营养并没有导致婴儿在住院期间的生长或身体组成的显著差异.
- 研究结果表明,早期增强的亲肠道营养可能不会对VLBW婴儿的早期生长轨迹或身体组成产生不利影响.
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