百日咳和成人百日咳相关并发症的流行病学:一位德国人声称数据分析
Bastian Surmann1, Julian Witte2, Manuel Batram1
1Vandage GmbH, Detmolder Straße 30, 33604, Bielefeld, Germany.
患有潜在疾病 (UCs) 的成年人面临更高的 pertussis 和其并发症的风险. 这凸显了在疫苗接种策略中考虑这些人的重要性,以预防百日咳和相关的严重后果.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 百日咳 (百日咳) 是一种高度传染性的呼吸道感染,影响所有年龄段的人.
- 关于成年人患有潜在疾病 (UCs) 的百日咳影响的证据有限.
- 这项研究检查了UCs和没有UCs的成年人中百日咳的发病率和并发症.
研究的目的:
- 调查UCs和没有UCs的成年人中百日咳的发病率.
- 确定UCs和没有UCs的成年人中 pertussis的并发症率.
- 评估与特定UCs相关的百日咳及其并发症风险.
主要方法:
- 德国索赔数据 (2015-2019年) 的回顾性分析.
- 匹配的队列分析用于发病率估计.
- 后勤和负二项式回归模型来评估风险和并发症率.
主要成果:
- 患有任何UC的成年人患上 pertussis 的风险高出1.72倍.
- 喘 (OR2.70),COPD (OR2.35) 和抑郁症 (OR2.08) 显示咳风险最高.
- 严重的并发症发生在13.4%的患有UC的 pertussis 患者中,而没有UC的患者则为9.5%.
结论:
- 患有某些UC的成年人患上百日咳和相关并发症的风险增加.
- 百日咳是成年人的重要传染病,影响有或没有UC的人.
- 疫苗接种建议应考虑患有UC的成年人,以预防百日咳及其并发症.
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