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Updated: Jul 4, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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通过驱动胺胺代谢,p53促进抗病毒天生的免疫力

Wenjun Xia1, Peng Jiang1

  • 1State Key Laboratory of Molecular Oncology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.

Cell reports
|January 31, 2024
PubMed
概括

瘤抑制剂p53通过增强胺生物合成途径 (HBP) 来增强抗病毒免疫力. 这种代谢重编程促进了对抗RNA病毒的干扰素-β (IFN-β) 生产.

关键词:
CP: 细胞生物学 细胞生物学CP: 免疫学 免疫学这是一种O-GlcNAcylation.UBXN1-MAVS信号传输系统提供信号.抗病毒天生的免疫力.赫克索胺的新陈代谢瘤抑制剂 p53 的作用.

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