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乌比奎丁E3结合酶BFAR促进PNPLA3的降解

Avash Das1, Haili Cheng1, Yang Wang1

  • 1Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390.

Proceedings of the National Academy of Sciences of the United States of America
|January 31, 2024
PubMed
概括

双功能性亡调节器 (BFAR) 针对含有帕塔丁类脂酶域蛋白3 (PNPLA3) 的降解,影响脂肪肝疾病的风险. 识别BFAR为管理PNPLA3水平和预防脂肪肝疾病提供了一个新的治疗标.

关键词:
肝细胞 肝细胞脂质滴滴滴滴滴滴滴滴滴滴滴滴滴突变是一种突变.蒸汽症是一种蒸汽症.无处不在的蛋白质酶体系统

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