埃塞俄比亚西北部系统性抗生素消费的六年趋势分析
Asrat Agalu Abejew1,2, Gizachew Yismaw Wubetu3, Teferi Gedif Fenta1
1Department of Pharmaceutics and Social Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
PloS one
|January 31, 2024
概括
埃塞俄比亚巴希尔达尔的抗生素消费在六年内显著下降了87.4%,这表明减少抗菌素耐药性的积极趋势. 然而,确保获得必需药物仍然对患者的治疗结果至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 药物监督 药物监督 药物监督
背景情况:
- 抗生素耐药性是一个关键的全球健康威胁,主要是由抗生素消费驱动的.
- 监测抗生素使用对于有效的抗菌素耐药性 (AMR) 制策略至关重要.
- 这项研究研究了埃塞俄比亚西北部的抗生素消费趋势.
研究的目的:
- 在六年内评估抗生素消费模式.
- 分析埃塞俄比亚制药供应局 (EPSA) 巴希尔达尔分公司使用抗生素的趋势.
- 为旨在打击抗菌素耐药性的战略提供数据.
主要方法:
- 从2016年7月到2022年6月的抗生素分配数据的回顾性分析.
- 利用世界卫生组织的解剖治疗分类 (ATC) 系统进行数据分类.
- 使用每1000名居民每天定义的每日剂量 (DID) 测量消费,并进行趋势分析.
主要成果:
- 总抗生素消耗量减少了87.4%,从2016/17年的6.9 DID降至2021/22年的0.9 DID.
- 大多数消费的抗生素 (77.1%) 来自"访问"类别,在"访问"和"观察"类别均有显著下降.
- 阿莫西西林,多西环素和西普罗夫洛克萨是最常用的抗生素,口服配方占主导地位.
结论:
- 研究区域的抗生素使用率较低且正在下降,这可能有助于减少AMR.
- 虽然减少消费对抗药性耐药性是积极的,但确保获得必要的抗生素对于患者的护理至关重要.
- 建议进行进一步的前性研究,以平衡AMR降低与最佳患者结果.
更多相关视频
06:54Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
Published on: July 19, 2024
1.0K
11:17Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
12.9K
相关概念视频
00:57Antibiotic Selection
53.6K
Overview
53.6K
01:27Combined Effects of Drugs: Synergism
3.9K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
3.9K
01:28Pulmonary Tuberculosis V
180
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
180