COVID-19疫苗接种与头发皮质醇度之间的关联
Yuemin Ding1,2,3,4, Yuxuan Xiong2, Jingru Zhao2
1Affiliated Hospital, Hangzhou City University, Linan, 311300, China.
Neuro endocrinology letters
|January 31, 2024
概括
接种COVID-19疫苗与头发皮质醇度 (HCC) 的变化有关,这是一个压力生物标志物. 接种疫苗的个体显示HCC水平发生变化,可能与不良反应有关,这表明疫苗接种对生理压力标志物产生影响.
科学领域:
- 内分泌学 在内分泌学.
- 心理神经免疫学 心理神经免疫学
- 公共卫生 公共卫生
背景情况:
- 皮质醇是一种关键的压力激素,可靠地通过头发皮质醇度 (HCC) 来测量.
- 慢性压力会提高皮质醇水平.
- 接种COVID-19疫苗对HCC的影响仍然没有研究.
研究的目的:
- 调查COVID-19疫苗接种与头发皮质醇度 (HCC) 之间的关联.
- 探索疫苗接种,压力水平和不良反应之间的关系.
主要方法:
- 收集了114名大学生 (57名接种疫苗,57名未接种疫苗) 的头发样本.
- 使用化学发光免疫测试 (CLIA) 测量HCC.
- 使用中国大学生心理压力表 (CCSPSS) 评估心理压力,并收集有关不良反应的数据.
主要成果:
- 没有接种疫苗的学生表现出比接种疫苗的学生更高的HCC水平.
- 接种疫苗的个体在最近的头发部分 (B部分) 与较旧的部分 (A部分) 相比,显示出显著更高的HCC.
- 接种疫苗的个体中HCC (ΔHCC) 的变化与接种疫苗状态和全身不良反应相关.
结论:
- 接种COVID-19疫苗会影响头发皮质醇度 (HCC).
- 观察到的HCC变化可能与接种疫苗后的全身不良影响有关.
- 这项研究强调了疫苗接种与生理压力标志物之间的潜在联系.
相关概念视频
Psychoneuroimmunology: Diabetes and Cancer
29
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
29
Psychoneuroimmunology: Cardiovascular Disease
31
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
31
Hypothalamic-Pituitary Axis
60.0K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
60.0K


