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在当代拉丁裔女孩队列中,经月经后生长模式
Ximena Gaete1, Pedro Ferrer-Rosende2,3, Ana Pereira2
1Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago, Chile, gaete.ximena@gmail.com.
Hormone research in paediatrics
|January 31, 2024
概括
健康的智利女孩在经期后4年内平均增长6.6厘米,其中大部分增长发生在第一年. 初潮的早期年龄与整体身高的增加有关.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 人类成长和发展 人类成长和发展
- 生物统计学 生物统计学
背景情况:
- 月经期意味着青春期发育和纵向生长的完成.
- 目前关于月经后 (PM) 增长模式的国家数据有限.
- 这项研究解决了关于智利女孩PM增长的最新信息的需求.
研究的目的:
- 为了前性地评估当代健康的智利女孩的月经后生长 (PM).
- 分析初经年龄和PM生长参数之间的关系.
- 建立PM增长轨迹的最新数据.
主要方法:
- 在GOCS队列中嵌入的前性队列研究.
- 在初潮后至少4年,每年对女孩进行随访.
- 使用转换和旋转 (SITAR) 模型的超叠加增长建模.
主要成果:
- 评估了534名女孩;可获得高达4年的身高数据,PM为364.
- 平均PM身高增长为6.6±2.5厘米,最大增长 (3.8±1.5厘米) 在第一年.
- 较早的初潮 (<11岁) 与较晚的初潮 (>13岁,4.4 ± 1.6厘米) 相比,与更大的身高增长 (8.2 ± 3.2厘米) 相关联 (p < 0.001).
- 初潮时的年龄显著影响了PM生长的大小,时间和强度,即使在调整了BMI之后.
结论:
- 女孩在经历月经后的4年内平均增长6.6厘米.
- 初经后的第一年显示出最显著的身高增长.
- 初潮时的年龄是绝经后生长模式的关键决定因素.
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