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Updated: Jul 4, 2025

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微生物生物衍生的酸盐通过基因素脱乙酶3限制了细胞分化,以调节肠道2型免疫力

Emily M Eshleman1, Taylor Rice1, Crystal Potter2

  • 1Division of Immunobiology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Immunity
|January 31, 2024
PubMed
概括

肠道微生物群调节肠道细胞,对2型免疫至关重要. 结合体细菌的代谢物,如丁酸盐,抑制了基因素脱乙酶3 (HDAC3) 的活性,控制了细胞分化和免疫反应.

关键词:
在 HDAC3 中,HDAC3 是黄油酸盐 黄油酸盐 是一种发展发展发展发展发展.表观遗传学是指表观遗传学.我们的肠道是肠道.我们的微生物群.这是一种有机物质的有机物质.干细胞是一种干细胞.状细胞的细胞.第二种类型的免疫.

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