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Updated: Jul 4, 2025

CD Spectroscopy to Study DNA-Protein Interactions
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Published on: February 10, 2022

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循环挤出Smc5/6组织转录诱导的阳性DNA超级卷

Kristian Jeppsson1, Biswajit Pradhan2, Takashi Sutani3

  • 1Karolinska Institutet, Department of Cell and Molecular Biology, Biomedicum, Tomtebodavägen 16, 171 77 Stockholm, Sweden; Karolinska Institutet, Department of Biosciences and Nutrition, Neo, Hälsovägen 7c, 141 83 Huddinge, Sweden; Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

Molecular cell
|January 31, 2024
PubMed
概括

Smc5/6复合物在正超卷区域挤出DNA循环,影响染色体组织. 这一发现揭示了Smc5/6在维持三维基因组结构方面的新机制.

关键词:
三维染色体组织在 ChIP-seqq.在DNA循环挤出过程中,在DNA plectoneme中使用.在DNA超级卷上.这就是Hi-C.在 Smc5/6/6 中使用.凝聚力 在凝聚力中收转录的收转录一个分子分析分析.

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