评估ulvan作为Solea senegalensis中的免疫营养素的作用
Marian Ponce1, Victoria Anguís1, Catalina Fernández-Díaz1
1IFAPA Centro El Toruño, Camino Tiro Pichón s/n, 11500, El Puerto de Santa María (Cádiz), Spain.
Fish & shellfish immunology
|January 31, 2024
概括
乌尔万是一种海洋多糖,在1%的饮食水平上增强了鱼类的免疫力,提高了对疾病的抵抗力. 较高剂量 (2%) 降低免疫功能,但1%的补充剂在戒断后显示持久的益处.
科学领域:
- 水产养殖营养水产养殖营养
- 海洋生物技术 海洋生物技术
- 免疫学 免疫学 免疫学
背景情况:
- 免疫营养提供了水产养殖中的预防策略.
- 乌尔万是一种海藻多糖,具有免疫调节性质.
- 塞内加尔 (Solea senegalensis) 是一个重要的水产养殖物种.
研究的目的:
- 为了评估Ulva ohnoi乌尔瓦提取物作为塞内加尔幼幼的免疫营养素的短期和长期影响.
- 评估ulvan对免疫基因表达和血免疫参数的影响.
- 为了确定Ulvan的最佳饮食水平,以抵抗疾病.
主要方法:
- 从U. ohnoi中提取Ulvan,使用热水和乙醇沉.
- 在体外分析乌尔万对塞内加尔独巨细胞的影响.
- 在体内养试验中,饮食补充了1%和2%的乌提取物.
- 挑战测试使用光细菌damselae亚种. piscicida (Phdp) 在养后和抽出后.
- 对和血免疫活动中的免疫基因表达的分析.
主要成果:
- 乌尔旺提取物在体外没有影响巨细胞活力和上调免疫基因表达.
- 饮食1%的乌尔万能增强免疫反应和短期抗病能力.
- 食2%的乌尔文降低了杀菌活性,并没有提供对Phdp的保护.
- 长期治疗 (戒药后30天),1%的Ulvan组显示免疫反应有所改善.
结论:
- 来自U. ohnoi的Ulvan可以作为水产养殖中的有效免疫营养素.
- 1%的食中含有乌尔旺可以增强塞内加尔幼鱼的抗病能力.
- 最佳剂量至关重要,因为更高的水平 (2%) 可以损害免疫功能.
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