高性能硫化聚乙烯硫/基托膜在化改进的化提高了肌素的运输
Retno Ariadi Lusiana1, Rahmad Nuryanto1, Nailul Muna1
1Department of Chemistry, Faculty of Science and Mathematics, Diponegoro University, 50275 Semarang, Indonesia.
International journal of biological macromolecules
|January 31, 2024
概括
修改过的聚硫 (PES) 膜与硫化,化和化显示出改善的水友性和增强的肌素运输用于血液透析应用.
科学领域:
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
- 化学工程是化学工程的重要组成部分.
背景情况:
- 聚乙硫 (PES) 膜具有理想的特性,如用于血液透析的机械强度和热稳定性.
- PES膜的固有疏水性限制了它们在运输肌素的效率,肌素是透析过程中消除的关键废物.
研究的目的:
- 通过改善肌素运输来提高PES膜用于血液透析的性能.
- 通过硫化和添加酸盐 (CS) 和化 (LiCl) 来修改PES膜.
主要方法:
- 使用硫化工艺对PES膜进行了修改.
- 酸盐 (CS) 和化 (LiCl) 被纳入了硫化PES膜 (SPES/CS-LiCl).
- 福利埃变换红外光谱法 (FTIR) 用于确认改造膜的成功制备.
主要成果:
- FTIR分析证实了修改后的SPES/CS-LiCl膜中存在硫酸盐,胺和基.
- 与纯粹的PES相比,经过修改的PES膜呈现出较高的多孔性,胀,吸水性和水友性.
- 肌素清除显著改善,从纯PES的0.30 mg/dL上升到SPES/CS-LiCl (5:2) 膜的0.42 mg/dL.
结论:
- 与CS和LiCl相结合的PES膜的硫化有效地增强了水友性和多孔性.
- 经过修改的SPES/CS-LiCl膜在肌素运输方面表现出卓越的性能,这使得它们对血液透析非常有希望.
- 这种修改策略提供了一个可行的途径,以提高血液透析膜的疗效.
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