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Updated: Jul 4, 2025

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
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Published on: June 28, 2018

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在EVI1+3q - 骨髓性白血病细胞中与EVI1表达相关的促剂中心色素相互作用

Han Leng Ng1, Mark E Robinson1,2, Philippa C May1

  • 1Department of Immunology and Inflammation, Faculty of Medicine, Centre for Haematology, Imperial College London, London, UK.

British journal of haematology
|January 31, 2024
PubMed
概括

骨髓性白血病中的EVI1表达,与3q变化无关,是由促进体相互作用驱动的,而不是增强体. 这一发现澄清了特定白血病亚型中EVI1基因调节的机制.

关键词:
在 EVI1 中.麦科姆是一个国家.染色素相互作用的相互作用增强剂是一种增强剂.瘤基因调节的规范

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Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells09:16

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells

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