我们在结核病的口罩下处理的是乳腺增生症吗? - 一个案例系列
Malavika Kottarathil1, Sudhabharathi Reju1, Ramya Barani1
1Department of Microbiology, Sri Ramachandra Institute of Higher Education and Research, India.
The Indian journal of tuberculosis
|January 31, 2024
概括
一种模仿结核病 (TB) 的疾病 - - 结核病 (Melioidosis) 在印度是流行病. 用PCR对Burkholderia pseudomallei进行早期诊断至关重要,特别是当结核病测试呈阴性结果时,可及时治疗和恢复.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
背景情况:
- 印度越来越多地发现有线性结核病,呈现出与结核病 (TB) 类似的症状.
- 性症的临床表现可以从肺部感染到败血症,往往导致误诊.
- 性症的危险因素包括2型糖尿病,慢性肺炎,高血压和葡萄糖皮质激素治疗.
研究的目的:
- 突出在流行地区模仿结核病的结核病 (melioidosis) 的诊断挑战.
- 强调PCR在诊断乳腺炎症的有用性,特别是在培养负的病例中.
- 倡导在常规检测结果为阴性时,对疑似结核病的患者进行结核病查.
主要方法:
- 三名怀疑患有肺外结核的男性患者的病例系列.
- 传统的嵌套PCR针对Burkholderia pseudomallei的16S-23S间距区域.
- 临床特征,风险因素和诊断测试结果的分析 (AFB涂抹,MTB GeneXpert,培养).
主要成果:
- 这三名患者都表现出类似结核病的症状,并具有相关的危险因素.
- 患者样本对B. pseudomallei的培养呈阴性,对结核病检测测试呈阴性.
- 传统的嵌套PCR在所有三名患者中都证实了B. pseudomallei,从而成功治疗了类素.
结论:
- 在特有地区结核病的差异诊断中应考虑结核病症,特别是在结核病工作结果为负的地区.
- 针对B. pseudomallei的PCR是诊断粉症的宝贵工具,特别是在培养负或接受抗生素治疗的患者中.
- 及时诊断和适当的抗生素治疗 (例如,第三代头素) 对于有机症的良好结果至关重要.
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