在轻微的COVID-19后,医护人员的注意力障碍和大脑活动变化
Keyi Lin1,2, Yaotian Gao1,2, Wei Ji1,2,3
1Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Brain imaging and behavior
|January 31, 2024
概括
医疗保健工作人员的2019年轻型冠状病毒病 (COVID-19) 损害了注意力,特别是指导和执行控制网络. 这与SARS-COV-2感染后特定的额头区域的大脑活动减少有关.
科学领域:
- 神经科学是一个神经科学.
- 传染性疾病 传染性疾病
- 认知心理学 认知心理学
背景情况:
- 严重急性呼吸道综合征冠状病毒2 (SARS-COV-2) 导致COVID-19,这是一种高度传染性和致病性疾病.
- 虽然许多COVID-19病例是轻微的,但经常观察到注意力障碍.
- SARS-COV-2 对注意力功能的确切影响尚不清楚.
研究的目的:
- 研究轻度COVID-19对注意力网络和大脑活动的影响.
- 为了比较医疗保健工作者与轻度COVID-19和健康对照者的认知功能和大脑活动.
主要方法:
- 使用注意力网络测试 (ANT) 来评估注意力功能.
- 使用静止状态功能磁共振成像 (rs-fMRI) 低频波动幅度 (ALFF) 来测量大脑活动.
- 包括45名轻度COVID-19的医疗保健工作者 (HCW) 和42名匹配的健康HCW.
主要成果:
- 患有轻度COVID-19的患者在导向和执行控制网络中表现出选择性损伤,但不是警报网络.
- 在患者组中发现了广泛的认知缺陷,包括注意力,记忆力和执行功能障碍.
- 与对照组相比,在患者组的左上部和中部前部旋转中观察到明显较低的ALFF值.
结论:
- SARS-COV-2 感染可能会降低左上和中额头回旋中的大脑活动.
- 这种减少的大脑活动可能会损害注意力定向和执行控制网络.
- 这些发现可能解释了COVID-19后在个人中观察到的注意力缺陷.
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