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Updated: Jul 4, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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Published on: October 27, 2020

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由SMYD2甲基转移酶诱导的细胞骨重塑驱动乳腺癌转移

Alexandre G Casanova1, Gael S Roth1,2, Simone Hausmann3

  • 1Grenoble Alpes University, CNRS UMR 5309, INSERM U 1209, Institute for Advanced Biosciences, Grenoble, France.

Cell discovery
|January 31, 2024
PubMed
概括

针对SMYD2,这是乳腺癌转移的关键调节器,提供了一个新的治疗策略. 抑制SMYD2阻断了癌细胞的扩散,通过破坏SMYD2-BCAR3-FMNL通路来改善生存率.

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