Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Dynamic reconfiguration of subunits from the hippocampal-amygdala complex indicate patterns of psychosis vulnerability in 22q11.2 deletion syndrome.

Scientific reports·2026
Same author

Shared and Individual Resting-State MEG Network Signatures of Tinnitus Revealed by Holistic Graph Learning.

IEEE open journal of engineering in medicine and biology·2026
Same author

The microstructure-weighted human connectome: network properties and structure-function correlations across spatial scales.

bioRxiv : the preprint server for biology·2026
Same author

Introducing a translationally relevant mouse model of radiosurgery-induced unilateral hearing loss.

Frontiers in neuroscience·2026
Same author

Auditory Brainstem Response as a Predictor of Hearing After Vestibular Schwannoma Radiosurgery.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·2026
Same author

A diffusion MRI-derived perivascular metric related to glymphatic-associated processes in bipolar disorder vulnerability: Multimodal correlates across emotion dysregulation patients and offspring.

Psychiatry research·2026

相关实验视频

Updated: Jul 4, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.0K

在本质震中发生thalamotomy后的动态功能变化取决于基线大脑形态测量.

Thomas A W Bolton1,2, Dimitri Van De Ville3,4, Jean Régis5

  • 1Department of Clinical Neurosciences, Neurosurgery Service and Gamma Knife Center, Centre Hospitalier Universitaire Vaudois, 1011, Lausanne, Switzerland. thomas.bolton@epfl.ch.

Scientific reports
|January 31, 2024
PubMed
概括

对于基本震 (ET) 进行的玛刀胸切除术可以改善大脑的功能连接. 动态功能连接和大脑形态测量预测在立体射线外科手术后的减少.

更多相关视频

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

9.2K
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

28.4K

相关实验视频

Last Updated: Jul 4, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.0K
Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

9.2K
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

28.4K

科学领域:

  • 神经科学是一个神经科学.
  • 放射性外科手术 放射性外科
  • 医疗成像医学成像

背景情况:

  • 基本震 (ET) 是一种神经疾病,通常用玛刀的立体辐射手术治疗,其目标是腹中中间核 (Vim).
  • 了解这种干预对大脑功能和结构的影响对于优化治疗结果至关重要.

研究的目的:

  • 调查玛刀法轮切除术 (SRS-T) 对耐药ET患者动态功能连接 (dFC) 和表面形态特征的影响.
  • 探索干预前大脑特征与治疗后临床改善之间的关系.

主要方法:

  • 休息状态fMRI用于分析23名ET患者在SRS-T前和1年后的dFC,并将其与健康对照 (HC) 进行比较.
  • 在34名ET患者中评估了基于表面的形态测量.
  • 统计分析检查了dFC状态的变化,与HC的形态相似性,以及它们与临床震减缓的相关性.

主要成果:

  • 在ET患者中,SRS-T增加了特定dFC状态 (状态1) 的空间稳定性.
  • 某些dFC状态的干预前表达 (状态3比状态1) 和在状态3中较低的空间可变性预测了更大的临床康复,家族ET患者的改善较小.
  • 在SRS-T后的13个大脑区域中,ET患者表现出与HCs的形态相似性减少,并且干预前的形态相似性与功能连接相似性相反相关,这种关系在治疗后正常化.

结论:

  • 左Vim功能动态与SRS-T后的震减轻直接相关.
  • 大脑形态测量在thalamotomy后调节这些功能动态方面发挥了支持作用.
  • 这些发现突显了SRS-T对基本震的治疗效果中的功能连接和大脑结构之间的相互作用.