血中阿迪波涅的水平和自闭症谱系障碍:一个系统的审查
Mohsan Ali1, Maha Kamran2, Muhammad Talha3
1King Edward Medical University, Lahore, Pakistan. mohsanali@kemu.edu.pk.
BMC psychiatry
|January 31, 2024
概括
患有自闭症谱系障碍 (ASD) 的儿童往往表现出较低水平的抗炎激素阿迪波涅丁. 这表明阿迪波内克丁和ASD严重程度之间存在潜在联系,需要进一步调查.
科学领域:
- 神经科学是一个神经科学.
- 免疫学 免疫学 免疫学
- 内分泌学 在内分泌学.
背景情况:
- 自闭症谱系障碍 (ASD) 涉及社会和沟通缺陷.
- 研究病理生理机制,包括免疫功能障碍,可能有助于早期的ASD诊断和治疗.
- 亚迪波涅丁,一种抗炎性亚迪波金和其他亚迪波金可能会影响ASD风险.
研究的目的:
- 审查阿迪波涅克丁水平与儿童自闭症谱系障碍 (ASD) 之间的关系.
- 探索阿迪波内克丁在ASD病理生理学和症状严重性的潜在作用.
主要方法:
- 在PubMed,Google Scholar和Cochrane数据库中进行系统的文献搜索,截至2022年9月.
- 关键词包括:阿迪波涅丁,阿迪波金,ASD,自闭症,自闭症障碍.
- 提取的数据主要集中在患有自闭症和没有自闭症的儿童之间皮素水平的平均差异上.
主要成果:
- 包括6项研究,其中4项表明ASD和阿迪波内克水平之间存在逆相关性.
- 两个积极的研究和一个负面的研究发现,与ASD严重程度相关的较低的阿迪波内克水平.
- 一项研究报告了微不足道的结果,突出发现的变化.
结论:
- 大多数审查的研究表明,在被诊断患有自闭症的儿童中,阿迪波涅丁水平较低.
- 较低的腺素水平也可能与自闭症症状的严重程度增加有关.
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