饮食障碍中的益生菌和益生菌干预:叙事性审查
Isabel Baenas1,2,3,4, Lucía Camacho-Barcia1,2,3, Romina Miranda-Olivos1,2,3,4
1Department of Clinical Psychology, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.
概括
治疗益生菌和益生菌治疗饮食障碍的证据有限,主要是神经性厌食症. 需要进一步的研究来确认它们对医疗结果的影响,并探索它们对心理症状的影响.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 精神病学是一个精神病学.
背景情况:
- 饮食障碍 (ED) 代表了复杂的心理健康状况,具有显著的身体健康影响.
- 肠道微生物群失生症越来越被认为是ED病理生理学的潜在因素.
- 益生菌和益生菌干预的目的是调节肠道微生物群的组成和功能.
研究的目的:
- 系统地审查和讨论当前关于饮食障碍治疗益生菌和益生菌干预措施的研究结果.
- 确定研究范围,并突出文献中关于ED群体中这些干预措施的空白.
主要方法:
- 在PubMed/MEDLINE,Cochrane图书馆和Web of Science进行了全面的文献搜索,直到2023年2月.
- 研究是根据PRISMA指南进行选择的,其中5项研究符合本叙述性综述的纳入标准.
- 该审查侧重于评估益生菌,益生菌或共生菌干预的随机对照试验.
主要成果:
- 所有包括的研究都专注于神经性厌食症 (AN),特别是在儿科和青少年群体.
- 益生菌干预措施 (例如,Lactobacillus reuteri,特定的酸奶) 显示了短期体重增加和免疫学参数的混合结果.
- 协生菌补充剂证明了改善微生物群多样性和减少炎症的潜力,尽管证据水平较低.
结论:
- 目前关于ED中益生菌和益生菌的研究很少,主要针对AN.
- 这些干预措施对AN医学和人体测量结果的有效性需要进一步的强有力的确认.
- 未来的研究应该调查益生菌和益生菌对心理症状和整体ED表现的影响,解决一个重要的文献差距.
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