通过使用瓶子组合计算器工具,尽量减少可预防的药物浪费
Ju Young Song1, Mark Wysocki1, Franklin Chen1
1Smilow Cancer Hospital, Yale-New Haven Hospital, New Haven, CT, USA.
概括
一台自动计算器显著减少了瘤药房的药物浪费和成本. 这种工具优化了药物瓶的选择,从而大大节省了成本高昂的药物的浪费,并将其降至最低.
科学领域:
- 制药科学 制药科学
- 卫生经济学 卫生经济学
- 瘤学 药房 实践
背景情况:
- 药物浪费,特别是高成本的瘤学和自身免疫疗法,构成了重大的财务挑战.
- 通常使用不同强度的单剂量瓶,增加了最佳药物选择的复杂性.
- 尽量减少可预防的药物浪费是医疗保健成本节约举措的关键目标.
研究的目的:
- 为了评估支持计算器在自动化小瓶选择中的有效性.
- 为了确定这种自动化是否可以通过尽量减少药物浪费来切实有效地降低制药支出.
- 评估对门诊药房设置的影响.
主要方法:
- 开发基于微软Excel的计算器,以自动化最佳的药物药瓶选择.
- 确定23种高成本的化疗和单克隆抗体药物作为最初的目标.
- 在瘤药房网络中传播和实施计算器,加上每月员工教育.
主要成果:
- 在2022财年,可预防的药物浪费价值减少了51% (412,300美元) 和子最佳瓶子选择减少了54% .
- 在2023财年,废弃物价值进一步减少了46% (183,400美元),次优选择减少了27%.
- 该自动化工具在11家门诊复合药房中显著减少了可预防的药物浪费和低于最佳的瓶子选择.
结论:
- 自动化瓶子选择工具是减少药品开支的实用和有效方法.
- 该计算器成功地减少了高成本药物领域的可预防药物浪费.
- 实施导致显著的成本节约和改善了门诊瘤药房的药物管理.
相关概念视频
01:15Two-Compartment Open Model: IV Infusion
234
A two-compartment model is a vital tool in pharmacokinetics, providing an essential understanding of drug behavior, especially for those administered via zero-order intravenous infusion. This model outlines two compartments: the central compartment, where elimination occurs, and the peripheral compartment.
The model illustrates the decrease in plasma drug concentration from the central compartment with a specific equation. It shows that under steady-state conditions, the drug's input rate...
The model illustrates the decrease in plasma drug concentration from the central compartment with a specific equation. It shows that under steady-state conditions, the drug's input rate...
234
01:15Drug Dosage Regimen: Overview
3.5K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.5K
00:56One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance
78
Clearance is a key pharmacokinetic parameter that quantifies the volume of body fluid from which a drug is entirely removed within a specific time frame. It is crucial in assessing how a drug is eliminated from the body and has critical clinical applications.
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
78
01:09One-Compartment Open Model for IV Bolus Administration: Estimation of Elimination Rate Constant, Half-Life and Volume of Distribution
253
The one-compartment open model is a simplified approach used in pharmacokinetics to understand the distribution and elimination of a drug administered through an intravenous bolus. This model assumes rapid drug dispersal throughout the body and elimination using a first-order process. Key pharmacokinetic parameters, such as the elimination rate constant (k), half-life (t1/2), and the apparent volume of distribution (Vd), can be estimated from this model. The elimination rate is calculated...
253