上部泌尿道骨外骨形成:一个意想不到的发现和不同的诊断考虑
Susan K Potterveld1, Nancy Wang2, Ankur R Sangoi1
1Department of Pathology, Stanford Medical Center, Stanford, CA, USA.
International journal of surgical pathology
|February 1, 2024
概括
在上部泌尿道,骨外骨形成或异型骨化很罕见. 这项研究报告了一例30岁男性病例,详细介绍了其组织学特征,并排除了特定的遗传标记.
科学领域:
- 尿路病理学 尿路病理学
- 不同类型的骨化异质化.
- 腎盆病理 腎盆病理 腎盆病理
背景情况:
- 在上泌尿道的骨外骨形成是一个不常见的发现,文献有限.
- 之前的报道仅限于针对结石进行皮肤透腎石切除的患者的小型临床系列.
- 这种现象的致病性,称为异型骨化,仍然不太了解.
研究的目的:
- 报告骨盆外骨形成的情况.
- 描述这个不寻常的发现的组织学特征.
- 通过辅助研究来调查潜在的遗传基础.
主要方法:
- 切除的尿道和骨组织的组织病理学检查.
- 组织骨下粘膜下结节的识别.
- 光现场混合化 (FISH) 用于MDM2放大和USP6重新排列.
主要成果:
- 组织学证实了骨和尿管中的粘膜下结节.
- 病人是一名30岁的男性,有结石病史.
- 对于MDM2放大和USP6重新排列,FISH研究是负的.
结论:
- 这一案例增加了在上泌尿道外骨形成的有限文献.
- 组织学发现将骨形成描述为粘膜下组织骨.
- 缺少MDM2放大和USP6重新排列表明这些遗传变化与这种特定呈现无关.
关键词:
骨头 骨头 骨头 骨头其他骨外组织.不同类型的异构形态 (heterotopia) 是一种异构形态.脏 脏 脏是什么?超塑性塑料 (metaplastic) 是一种金属塑料.骨盆 骨盆 骨盆 骨盆脏 脏的 脏尿路器是尿路器的更多相关视频
06:39Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
Published on: November 22, 2019
7.7K
06:05Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection
Published on: October 12, 2017
15.7K
相关概念视频
01:20Disorders of the Urinary System
309
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
309
01:22Ureters
491
The ureters are retroperitoneal tubes located on either side of the vertebral column. They are responsible for transporting urine from each kidney to the urinary bladder. These tubes have thick walls and are approximately 25-30 cm long. Their diameter is around 10 mm at the renal pelvis, gradually narrowing to 1 mm as the ureter obliquely enters the posterior bladder wall through the ureteric orifices. The shape of these orifices is slit-like, which helps to prevent urine backflow toward the...
491