选择的致病性和非致病性细菌的水性臭氧失活动力学,以验证净化水中的最低使用量
Yuqian Lou1, David R Kasler2, Zach L Hawkins2
1PepsiCo R&D, Valhalla, NY, United States.
Frontiers in microbiology
|February 1, 2024
概括
臭氧有效地使净化水中的细菌无活化,Ct剂量为0.832,确保对测试的病原体减少5日志. 菌 (Enterococcus faecium) 作为一个可靠的替代品,用于验证臭氧清除水污染过程.
科学领域:
- 处理水处理水处理水处理
- 微生物学 微生物学
- 化学消毒 化学消毒 化学消毒
背景情况:
- 臭氧是净化水处理中的关键抗菌剂.
- 美国FDA的规定限制瓶装水中的残留臭氧为0.4mg/L.
- 非结肠杆菌病原体可能会污染瓶装水,需要对臭氧的有效性进行测试.
研究的目的:
- 研究臭氧对净化水中的致病性和非致病性细菌的疗效.
- 为了确定监管的臭氧水平是否能确保产品对更广泛的细菌的安全.
- 开发臭氧失活剂量与反应关系的预测模型.
主要方法:
- 细菌失活被研究为臭氧剂量 (Ct单位) 的函数.
- 测试的物种包括菌,大肠杆菌,Listeria monocytogenes,Pseudomonas aeruginosa和沙门氏菌.
- 使用一种新的统计方法来分析剂量反应数据并确定下限.
主要成果:
- 剂量反应关系大多是线性的,但是异构的.
- 制定了一个95%的信心下限方程:Logpopulation减少 = 3.80Ct + 1.84.
- 在21°C时0.832的臭氧Ct可以实现所有测试细菌的≥5-log减少.
结论:
- 在Ct 0.832的臭氧应用确保了净化水中的广谱细菌失活.
- 菌 (Enterococcus faecium ATCC 8459) 是一个合适的替代品,用于验证臭氧净化水的有效性.
- 这些发现支持在净化和潜在的其他水类处理验证中实施臭氧.
关键词:
在Ct值中,值为t.肠球菌 (Enterococcus faecium) 是一个有毒的菌株.数据建模数据建模不同的性 异质的性臭氧层中的臭氧.致病性细菌是一种致病性细菌.净化过的水 净化过的水水病原体的替代品更多相关视频
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