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胆固醇疾病中微RNA和氧化应激之间的交叉关系

Filippo Pelizzaro1,2, Romilda Cardin1, Giulia Sarasini1

  • 1Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.

Inflammatory intestinal diseases
|February 1, 2024
PubMed
概括

氧化应激和microRNAs (miRNAs) 与乳病 (CeD) 有关. 本综述阐明了它们在成年人中的作用和相互作用,并介绍了关于miRNA调节CeD病变的新试点研究结果.

关键词:
结肠病是什么?结肠病是什么?诊断 诊断 诊断 诊断 诊断炎症 炎症是一种炎症.微RNAs是一种微RNA.氧化应激是一种氧化应激.

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MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
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