在侧半圆通道发育不良症的前庭功能障碍
Ji Min Yun1, Sung Huhn Kim1, Seong Hoon Bae2
1Department of Otorhinolaryngology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Frontiers in neurology
|February 1, 2024
概括
侧半圆通道 (LSCC) 形,一个常见的内耳形,可以损害前庭功能. 在LSCC发育不良症中缺少中央骨岛 (CBI) 与降低前庭眼反射 (VOR) 功能有关.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
- 医疗成像医学成像
背景情况:
- 侧半圆通道 (LSCC) 形是最常见的内耳形.
- LSCC发育不良的频谱从轻微缩短到完全缺失中央骨岛 (CBI).
- 在LSCC发育不良和前庭功能缺陷之间的关系仍未得到充分研究.
研究的目的:
- 调查LSCC发育不良和前庭功能之间的关联.
- 为了比较患有和没有中央骨岛 (CBI) 的患者的前庭功能,在存在LSCC发育不良的情况下.
主要方法:
- 对17名患有LSCC发育不良的患者 (23个耳朵) 的回顾性分析.
- 使用热量测试和视频头脉冲测试 (vHIT) 评估前庭功能.
- 带有和没有中央骨岛 (CBI) 的耳朵之间的前庭功能参数的比较.
主要成果:
- 在69%的患者中发现了热量测试中的异常,而92%的患者在vHIT上显示了正常的LSCC前庭眼反射 (VOR) 增加.
- 在热量测试慢相速度和LSCC VOR增益 (r=0.792,p=0.004) 之间观察到显著的相关性.
- 没有中央骨岛 (CBI) 的耳朵与CBI (分别p=0.001和p=0.004) 的耳朵相比,表现出明显较低的慢相速度和LSCC VOR增长.
结论:
- 这种LSCC发育不良会对前庭眼镜反射 (VOR) 功能产生负面影响.
- 在LSCC发育不良症中缺少中央骨岛 (CBI) 与更显著的前庭功能障碍有关.
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