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纳米颗粒对人类健康和疾病的影响

Bedanta Roy¹, Karthikeyan Murugesan², Maghimaa Mathanmohun³

¹Associate Professor, Department of Physiology, Faculty of Medicine, Quest International University, No. 227, Plaza Teh Teng Seng (Level 2), Jalan Raja Permaisuri Bainun, 30250 Ipoh, Perak Darul Ridzuan, Malaysia.

Nepal journal of epidemiology

|February 1, 2024

概括

纳米粒子 (NP) 在医学和工程方面提供了独特的好处,但也带来了重大的健康和环境风险. 了解NP毒性机制对于减轻其有害影响至关重要.

科学领域:

材料科学材料科学材料科学
毒理学毒理学毒理学
纳米技术纳米技术

背景情况:

纳米粒子 (NP) 由于其独特的特性,如小尺寸和量子效应,在医学和工程中得到广泛的应用.
它们的应用包括药物输送,疫苗生产和血管疾病的治疗,这是由于其增强的生物可用性和准能力.

研究的目的:

调查与纳米粒子使用相关的重大健康和环境风险.
阐明NP诱导的细胞损伤和毒性的机制.

主要方法:

对有关纳米粒子特性和应用的现有文献进行审查.
分析详细介绍NP与生物系统和细胞通路相互作用的研究.
检查NP进入人体的途径及其在器官中的积累.

主要成果:

核可以通过血破裂,细胞亡和自细胞死亡诱导细胞死亡,从而导致炎症.
吸入,摄入和与皮肤接触是主要的暴露途径,NP在呼吸系统中积累.
这些NP与肺炎,纤维化,内分泌干扰,DNA损伤和男性不孕症有关.

结论:

纳米粒子具有双重用途的潜力,提供治疗优势,同时造成相当大的健康和环境危害.
进一步的研究,特别是生态学家和流行病学家之间的跨学科合作,对于开发减轻NP毒性的策略至关重要.

关键词:

细胞细胞的细胞.影响力是影响力.纳米颗粒是一种纳米粒子.信号信号是指一个信号.毒性的毒性毒性的毒性

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