多中心研究验证了在血液透析患者的住院风险评估工具
Muhammad Nauman Hashmi1, Hammad Raza1, Muhammad A Khan2,3,4
1Hemodialysis, Ministry of National Guard Health Affairs, Jeddah, SAU.
Cureus
|February 1, 2024
概括
一个具有成本效益的工具有效地识别了患有慢性病的营养不良患者,他们面临住院和死亡的高风险. 在多个中心进行的验证证实了其在透析装置中的实用性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床营养学 临床营养学
- 公共卫生 公共卫生
背景情况:
- 蛋白质能量浪费 (PEW) 在慢性病 (CKD) 患者中很常见.
- 早期识别PEW对于管理CKD并发症至关重要.
- 现有的风险评估工具可能缺乏易于应用或成本效益.
研究的目的:
- 为了验证哈什米的工具对PEW在维护血液透析 (HD) 患者的风险评估.
- 评估该工具在多个中心的适用性和成本效益.
- 为了将风险得分与住院和死亡率相关联.
主要方法:
- 这是一项多中心验证研究,涉及868名维护性HD患者,持续了两年.
- 利用哈什米的工具,评分诸如BMI,高强度复古,白蛋白和并发症等变量.
- 患者被分为低风险 (<6) 和高风险 (≥6) 组;结果使用基平方测试进行比较.
主要成果:
- 哈什米的工具确定了439名高风险和429名低风险患者.
- 高风险患者,特别是糖尿病和高血压患者,住院率显著增加 (血管患者p=0.036,非血管患者p<0.001).
- 高风险组的死亡率是高风险组的三倍 (p<0.001).
结论:
- 哈什米的工具是一种经过验证,简单且具有成本效益的方法,用于识别有风险的营养不良的CKD患者.
- 该工具准确地预测了维护性疾病患者的住院和死亡率.
- 这种多中心验证支持其在沙特阿拉伯各地透析单位的广泛使用.
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