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Updated: Jul 4, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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在内皮机械传导中对YAP促进器可访问性的规范

Aarren J Mannion1,2, Honglei Zhao1, Yuanyuan Zhang1

  • 1Departments of Oncology-Pathology (A.J.M., H.Z., Y.Z., L.H.), Karolinska Institute, Stockholm, Sweden.

Arteriosclerosis, thrombosis, and vascular biology
|February 1, 2024
PubMed
概括

机械力量通过AmotL2和表观遗传变化调节内皮细胞YAP转录,维持血管平衡. 这一途径对细胞增殖至关重要,可能解释AmotL2删除模型中的动脉瘤形成.

关键词:
在 YAP 信号中使用 YAP 信号.大动脉的动脉.细胞结节 细胞结节在这种情况下,染色染色素内皮细胞是内皮细胞.表观遗传调节 表观遗传调节核膜是一种核膜.

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