波利:用于基因型微卫星的R包,并从短读数据中检测高度多态DNA标记物的R包

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Updated: Jul 4, 2025

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Annabel Perry1,2, Dirk Eddelbuettel3, Gil Rosenthal2,4

  • 1Department of Human Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.

Molecular ecology resources
|February 1, 2024
PubMed
概括

波利,一个R包,准确地基因型微卫星和检测多态变体使用短读数据. 该工具通过克服当前基因定型方法的局限性,增强了人群遗传学研究.

关键词:
保护遗传学保护遗传学生态遗传学 生态遗传学基因型 基因型 基因型微卫星微卫星是什么意思人口遗传学 经验性遗传学

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Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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