在澳大利亚使用公共补贴的TAPENTADOL的质量:基于人口的分析分析
Ximena Camacho1,2, Andrea L Schaffer1,2,3, Jonathan Brett1,2,4
1School of Population Health, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.
Internal medicine journal
|February 1, 2024
概括
澳大利亚的持续释放型塔达尔使用,虽然往往是短期的,但尽管阿片类药物趋势下降,但开始使用的次数越来越多. 还观察到向私人销售的转变,表明处方模式发生了变化.
科学领域:
- 药理学和药理学流行病学
- 疼痛管理疗法治疗方法
- 吸食阿片类药物的使用研究研究
背景情况:
- 持续释放 (SR) tapentadol 在2014年被列入澳大利亚制药福利计划 (PBS) 治疗慢性严重疼痛.
- 尽管其他阿片类药物的使用趋势下降,但塔达尔的发行量有所增加.
- 人们担心SR阿片类药物的依赖和过量服用风险增加,特别是在急性疼痛方面.
研究的目的:
- 调查澳大利亚政府补贴的tapendadol的质量使用情况.
- 分析塔潘塔多尔开始和发放模式的趋势.
主要方法:
- 从10%的可接受PBS的澳大利亚人 (2014-2021) 随机抽样中分析发行记录.
- 对SR tapentadol的年度启动率和使用模式的检查.
- 使用国家销售数据来确定销售中PBS所覆盖的比例.
主要成果:
- 塔潘塔多尔的开始在2019年达到峰值 (7.5/1000人群),到2021年下降 (5.3/1000人群).
- 超过92%的新用户在第一年内停止服用塔达尔; 58%的新用户只服用了一次药物.
- 从2020年6月开始,出现了显著的转变,PBS补贴销售额从69.1%下降到63.9%.
结论:
- 塔潘塔多尔 (SR) 似乎主要用于短期使用.
- 虽然大部分的塔潘塔多尔销售仍然受到PBS补贴,但明显的是私人销售的趋势.
- 这些发现表明,需要持续监测塔达尔的处方和使用模式.
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