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Updated: Jul 4, 2025

Quantitative Proteomics Workflow using Multiple Reaction Monitoring Based Detection of Proteins from Human Brain Tissue
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绘制人类大脑蛋白质组:机遇,挑战和临床潜力

Paz Cartas-Cejudo1, Adriana Cortés1, Mercedes Lachén-Montes1

  • 1Clinical Neuroproteomics Unit, Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.

Expert review of proteomics
|February 1, 2024
PubMed
概括

描述人类大脑的分子概况是理解大脑专业化和神经退行等疾病的关键. 先进的蛋白质组学为识别精神和神经疾病的生物标志物和潜在药物标提供了新的途径.

关键词:
脑子 脑子 脑子 脑子生物标志物 生物标志物大脑脊髓液中的脑脊液.药物重新定位 药物重新定位质谱学质谱学是指质谱学.蛋白质组学 蛋白质组学目标 目标 目标 目标

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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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