超声导向的Lipiodol®歇斯托索平学:关于怀孕和并发症率的前性研究
Glen Lo1,2,3,4, Dana Hince5, Neil Johnson6,7,8
1Western Ultrasound For Women, Perth, Western Australia, Australia.
The Australian & New Zealand journal of obstetrics & gynaecology
|February 1, 2024
概括
使用Lipiodol®的超声波导向囊造影 (HSG) 对于生育能力评估是安全的. 怀孕率与旧方法相似,但由于亚临床甲状腺功能低下的风险,监测甲状腺功能至关重要.
科学领域:
- 生殖医学 生殖医学
- 医疗成像医学成像
- 内分泌学 在内分泌学.
背景情况:
- 使用Lipiodol®的光学合镜 (HSG) 已被确立用于生育治疗.
- 超声波越来越喜欢HSG由于改善了患者的舒适性和缺乏电离辐射.
- 超声导向Lipiodol® HSG的安全性和有效性仍在调查中.
研究的目的:
- 用超声波引导的Lipiodol® HSG来前性评估怀孕和并发症的发生率.
- 评估这种新型成像技术在患有不明原因不孕症的女性中的安全性.
主要方法:
- 一个单一中心的前性研究,涉及有原因不明的不孕症的女性.
- 在初始的输卵管通透性确认后,进行了超声波引导的Lipiodol®子宫洗和输卵管冲洗.
- 术后记录了怀孕结果,甲状腺功能和疼痛评分.
主要成果:
- 招募了52名女性,其中45名女性完成了手术.
- 怀孕率包括57%的生物化学,53%的临床和35%的持续怀孕在六个月.
- 亚临床甲状腺功能低下症发生在41%的参与者中;在HSG手术期间发现了一例静脉注射. 没有观察到过敏反应或栓塞等严重不良事件.
结论:
- 门诊超声波引导的Lipiodol® HSG证明了安全性和与光镜方法相比的怀孕率.
- 血管内和亚临床甲状腺功能低下的发病率反映了先前的发现,强调了甲状腺功能监测的重要性.
- 超声导向的Lipiodol® HSG代表了一种可行的替代成像方式来评估生育能力.
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