荷兰偏头痛队列中的物质使用与一般人口相比
Thomas C van den Hoek1, Iris E Verhagen1, Irene de Boer1
1Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands.
Headache
|February 1, 2024
概括
与普通人群相比,偏头痛患者使用的非法药物较少,吸烟少,饮酒少. 然而,慢性偏头痛患者使用更多的非法药物和吸烟比偶发性偏头痛患者更多.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 生活方式因素,包括物质使用,越来越多地被认为是偏头痛触发者的潜在作用.
- 了解偏头痛患者的物质使用模式对于全面的患者护理和触发因素识别至关重要.
研究的目的:
- 调查和比较被诊断患有偏头痛的个人与普通人群之间的自我报告的物质使用情况.
- 分析情节性偏头痛 (EM) 和慢性偏头痛 (CM) 亚组之间物质消费模式的差异.
主要方法:
- 一大群荷兰偏头痛患者 (n=5176) 和荷兰一般人口的代表样本 (n=8370) 完成了物质使用调查.
- 偏头痛患者被分为情节性偏头痛 (EM) 和慢性偏头痛 (CM) 组.
- 对一般人群和偏头痛患者的药物消费量进行了比较,以及对EM和CM子组的药物消费量进行了比较,并对性别和教育水平进行了调整.
主要成果:
- 与普通人群相比,偏头痛患者报告的非法药物使用率 (OR 0.48),当前吸烟率 (OR 0.60),终身吸烟率 (OR 0.75) 和当前酒精消费率 (OR 0.66) 显著降低.
- 与EM患者相比,CM患者的非法药物使用率 (OR 1.73) 和目前的吸烟率 (OR 1.61) 较高,但酒精消费率较低 (OR 0.54).
- 在CM和EM患者的吸烟史中没有发现显著差异 (OR1.18).
结论:
- 与普通人群相比,偏头痛患者使用非法药物,吸烟或饮酒的可能性较低.
- 慢性偏头痛患者表现出明显的物质使用情况,其特点是与偶发性偏头痛患者相比,非法药物和吸烟率较高,酒精消费量较低.
相关概念视频
Substance Use Disorders Affecting Sleep
167
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
167
Stress and Mental Health
157
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
157
Drug Dependence
1.0K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.0K
Drug Abuse and Addiction: Pharmacological Phenomena
476
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
476
Stimulants
197
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
197
Observational Studies
8.6K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
8.6K


