主动/被动吸烟与自发早产之间的关系:来自多中心研究的数据
F S Cavichiolli1, A Borovac-Pinheiro1, G J Lajos1
1Department of Obstetrics and Gynecology, School of Medicine, University of Campinas, Campinas, São Paulo, Brazil.
概括
这项研究发现,怀孕期间吸烟与自发早产之间没有确定的联系. 无论是主动吸烟还是被动吸烟,都没有增加自发早产或新生儿不良后果的发生率.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿健康 新生儿健康
- 公共卫生 公共卫生
背景情况:
- 过早生育是导致5岁以下死亡的主要原因,吸烟是已知的危险因素.
- 确立吸烟与自发早产 (SPB) 之间的具体联系仍然具有挑战性.
- 了解主动和被动吸烟对SPB的影响对于母婴健康至关重要.
研究的目的:
- 调查主动和被动吸烟与自发早产之间的关联.
- 分析社会人口统计,出生和新生儿数据,与怀孕期间的吸烟状况相关.
主要方法:
- 一个多中心的,在20家巴西产科医院 (2011-2012) 进行的横截面研究.
- 包括5295名孕妇参与者及其早产婴儿.
- 使用频率,百分比,千二测试和逐步比较的统计分析.
主要成果:
- 13.5%的孕妇是活跃吸烟者,31.6%的人接触过被动烟.
- 与非吸烟者 (48.4%) 相比,在活跃吸烟者 (61.2%) 和被动吸烟者 (61.2%) 中观察到SPB的更高发病率.
- 多变量分析没有确定吸烟和SPB之间的因果关系.
结论:
- 该研究没有证实由于怀孕期间吸烟增加了自发早产的风险.
- 被动吸烟暴露与SPB的发病率增加或新生儿不良后果无关.
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