补充omega-3可以减少儿童的精神分裂性人格:一项随机对照试验
Adrian Raine1,2,3, Ruben C Gur2,4,5, Raquel E Gur2,4,5
1Department of Criminology, University of Pennsylvania, Philadelphia, PA, USA.
补充omega-3可以降低11-12岁儿童的精神分裂症. 这种干预,结合认知行为疗法,在减少精神分裂型人格特征方面显示出持久的好处.
科学领域:
- 神经科学是一个神经科学.
- 儿童心理学 儿童心理学
- 营养精神病学 营养精神病学
背景情况:
- 以前的研究表明,omega-3脂肪酸可能会减少精神分裂症.
- 早期儿童 (3-5岁) 增加鱼类消费的先前干预与23岁时分裂型人格减少相关.
研究的目的:
- 测试一种假设,即omega-3补充剂可以减少儿童的精神分裂症.
- 研究单独和与认知行为疗法 (CBT) 结合的omega-3补充剂的疗效.
主要方法:
- 一个随机,单盲,分层,因数试验,涉及290名11-12岁儿童.
- 参与者被分配到只有欧米茄-3,只有CBT,欧米茄-3+CBT或对照组.
- 在基线,3个月,6个月和12个月使用儿童分裂型人格问卷 (SPQ-C) 评估精神分裂.
主要成果:
- 一个显著的群体 × 时间相互作用显示,治疗后和停止3个月后,Omega-3 Only和Omega-3 + CBT组的总精神分裂性得分降低了.
- 与仅CBT相比,在omega-3组治疗后9个月观察到人际分裂型的减少.
- 较高的基线饮食omega-3摄入量与较强的精神分裂型减少相关.
结论:
- 补充omega-3似乎有效地减少了儿童的精神分裂个性.
- 研究结果表明,omega-3在早期预防晚年青少年精神分裂特征方面具有潜力.
- 结果需要进一步的研究和对早期干预策略的潜在公共卫生影响.
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