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华盛顿州金县的克拉米迪亚形虫病治疗处方实践的趋势,2010-2018年
Piper R Brase1, Julia C Dombrowski, Anna Berzkalns2
1From the Department of Epidemiology, University of Washington, Seattle, WA.
Sexually transmitted diseases
|February 1, 2024
概括
在2021年指导方针之前,对Chlamydia trachomatis (CT) 的阿兹罗密辛处方增加了,而多西环林的使用减少了. 这一趋势凸显了提供者教育需要与新的一线多西环林治疗建议保持一致的需要.
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 抗微生物药物管理委员会
背景情况:
- 2021年,国家克拉米迪亚肌肉病 (CT) 治疗指南发生了转变,优先考虑了多西环林而不是阿齐思罗米.
- 在CT处方实践中,指南之前的趋势并未得到充分理解.
研究的目的:
- 分析2021年指南变更之前的克拉米迪亚形虫处方实践的趋势.
- 为了确定与在CT治疗中使用阿齐思罗米相关的因素.
主要方法:
- 华盛顿州STD监测数据 (2010-2018) 的趋势分析,用于金县的女性CT病例.
- 按设施类型对处方趋势的描述性分析和Poisson回归用于与阿齐思罗米接收相关的病例特征.
主要成果:
- 治疗CT的阿兹罗密辛使用率从2010年的86%增加到2018年的94%,而多西环林的使用率从13%降至5%.
- 截至2018年,大多数设施类型的阿齐思罗米使用率高 (>95%).
- 较年轻的病例和有色人种病例更有可能接受亚齐菌素.
结论:
- 为了满足当前的CT治疗指南,需要在处方方面做出重大转变.
- 针对性提供者教育对于促进过渡到多西环林治疗至关重要.
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