hGBP3的螺旋域不能刺激GTP的第二次酸盐裂解

Divya Rashmi1, Sowmiya Gupta1, Tasneem Kausar1

  • 1Protein Engineering Laboratory, National Institute of Immunology, New Delhi, India.

概括

人体酸结合蛋白 (hGBPs) 是免疫的关键. 与hGBP1不同,hGBP3由于其催化域缺乏构造变化,导致GMP产生减少,从而阻碍了其抗病原和抗瘤功能.

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