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Updated: Jul 4, 2025

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice

Published on: March 24, 2017

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赛迪拉尼布通过上调IRF-1来增强MHC-I的转录

Jie Zhang1, Hongjie Guo1, Longsheng Wang1

  • 1Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology and Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Biochemical pharmacology
|February 1, 2024
PubMed
概括

赛迪拉尼布通过激活IRF-1通路,在瘤细胞中增强主要基因相容性复合物I类 (MHC-I) 表达. 这种上调增强了抗瘤免疫力,并改善了对免疫治疗的反应.

关键词:
这就是Cediranib.在 IRF-1 中,IRF-1 是一个 IRF-1 函数.免疫治疗是一种免疫疗法.在MHC-I中,MHC-I是最重要的.在PD-L1中.

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