典型心房的导管切除后心房的发生率和模式 - - FLUTFIB研究
Philipp Attanasio1, Tabea Budde1, Paul Kamieniarz1
1Deutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.
概括
心房动 (AF) 经常发生在心房动 (AFL) 切除后,大多数发作无症状且持续时间长. 这些发现指导了洞穴椎间盘 (CTI) 切除后的抗凝管理.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 医疗器械 医疗器械
背景情况:
- 卡沃特里克斯皮德 (Cavotricuspid) 缺口 (CTI) 切除有效地治疗心房动 (AFL).
- 在CTI切除后,心房动 (AF) 可能会发生,需要进一步的治疗.
- 持续的心脏监测对于检测亚临床心律失常至关重要.
研究的目的:
- 为了确定AF的发病率,持续时间,时间和症状,在AFL的CTI切除后进行AF.
- 评估植入式循环记录器 (ILR) 在检测AF后移除的实用性.
- 根据CTI切除后的抗凝策略提供信息.
主要方法:
- 在没有先前AF诊断的情况下,针对AFL进行CTI切除的100名患者的前性研究.
- 使用植入式循环记录器 (ILR) 进行持续的心脏监测,平均24个月.
- 分析AF发作特征,症状和基线预测因素.
主要成果:
- 77%的患者在切除后发生了AF,平均发病时间为180天.
- 大多数AF发作 (>58%) 持续时间超过1小时,52%无症状.
- 基线分数 (HATCH,CHA2DS2-VASc) 没有预测AF的发展;没有发生中风或TIA.
结论:
- 植入式循环记录器显示,在CTI切除后,AF的发病率很高,通常是无症状和长时间的.
- 这些发现支持需要仔细考虑这些患者的抗凝管理.
- 这项研究为未来关于AF发作持续时间和抗凝剂启动的试验提供了关键数据.
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