植物模式识别受体的进化轨迹
Bruno Pok Man Ngou1, Michele Wyler2, Marc W Schmid2
1RIKEN Center for Sustainable Resource Science, Yokohama, Japan.
Nature communications
|February 1, 2024
概括
植物免疫受体 (LRR-RLPs) 从生长调节受体 (LRR-RLK-Xb) 进化,具有共同的起源. 这项研究揭示了这些细胞表面受体如何多样化以检测环境适应的各种信号.
科学领域:
- 植物生物学 植物生物学
- 进化生物学是进化的生物学.
- 分子遗传学 分子遗传学
背景情况:
- 细胞表面受体对于免疫,发育和繁殖至关重要.
- 对于受体专业化的进化途径在很大程度上是未知的.
- 了解植物免疫受体进化是农业和环境科学的关键.
研究的目的:
- 研究植物中免疫特异性氨酸丰富的重复受体样蛋白 (LRR-RLPs) 的进化起源.
- 阐明植物免疫和发育调节细胞表面受体之间的关系.
- 揭示驱动受体多样化的分子机制,以适应环境.
主要方法:
- 从350个植物基因组中分析了超过20万个细胞表面受体基因.
- 遗传学分析以追踪LRR-RLPs的进化史.
- 受体域的功能性表征 (果汁膜,跨膜,细胞结核激酶域).
主要成果:
- LRR-RLPs与LRR受体类激酶 (RLK) 亚组Xb具有共同的进化起源,该亚组调节植物生长和发育.
- 在LRR-RLPs中共同受体相互作用的关键动机与LRR-RLK-Xb中的关键动机有关.
- LRR-RLPs通过柔膜/跨膜区域启动免疫;LRR-RLK-Xb通过激酶域调节发展.
结论:
- 参与免疫和发育的植物细胞表面受体具有共同的进化起源.
- 受体区域的多样化允许识别不同的信号和激活特定的反应.
- 这种进化机制使植物能够通过感知各种外部信号来适应不断变化的环境.
相关概念视频
01:25Cell Signaling in Plants
5.6K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.6K
02:00Photoreceptors and Plant Responses to Light
20.3K
Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.
20.3K
01:11Channel Rhodopsins
2.6K
Most organisms use photoreceptors to sense and respond to light. Examples of photoreceptors include bacteriorhodopsins and bacteriophytochromes in some bacteria, phytochromes in plants, and rhodopsins in the photoreceptor cells of the vertebral retina. The light-sensitive property of these receptors is because of the bound chromophores, such as bilin in the phytochromes and retinal in the rhodopsins.
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
2.6K
02:26Defenses Against Pathogens and Herbivores
23.7K
Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
23.7K
01:28Diversity of Antigen Receptors
589
Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
589
01:22Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K