在SARS-CoV-2感染后儿童的肺功能:系统性审查和元分析
Elham Bakhtiari1, Nasrin Moazzen2,3
1Clinical Research Development Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
BMC pediatrics
|February 2, 2024
概括
长期的COVID在儿童中可能会出现呼吸系统症状,如咳和呼吸障碍. 然而,肺功能测试显示SARS-CoV-2感染后没有异常.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
背景情况:
- 人们对SARS-CoV-2感染后儿童的长期呼吸道并发症存在担忧.
- 在儿科患者中评估COVID-19后的呼吸系统健康对于了解长期结果至关重要.
研究的目的:
- 系统地审查和元分析SARS-CoV-2感染后儿童的呼吸系统症状和肺功能.
- 评估呼吸系统症状的患病率和评估COVID-19小儿幸存者的螺旋测量参数.
主要方法:
- 系统的文献搜索进行到2023年3月30日.
- 包括专注于COVID-19后儿童呼吸系统症状和肺功能的研究.
- 对于关键结果,计算了聚合平均值和95%置信区间 (CI).
主要成果:
- 分析了涉及386名儿科患者的8篇文章.
- 常见的症状包括呼吸不全,咳,运动不耐受和疲劳.
- 分析结果显示,常规的螺旋计参数,包括强迫呼吸量 (FEV1),强迫生命能力 (FVC),FEV1/FVC比率,以及一氧化碳的扩散能力,在支气管扩张后没有显著变化.
结论:
- 尽管存在一些呼吸系统症状,但儿童在SARS-CoV-2感染后通常表现出正常的肺功能.
- 疾病的严重程度和先前存在的喘似乎没有影响这些肺功能结果.
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