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Updated: May 10, 2026

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
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Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform

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Cirscan:一种闪亮的应用程序,用于识别差异活跃的海绵机制,并可视化circRNA-miRNA-mRNA网络

Rose-Marie Fraboulet1, Yanis Si Ahmed1, Marc Aubry2

  • 1Univ Rennes, CNRS, INSERM, IGDR (Institut de Genetique et Developpement de Rennes) - UMR 6290, ERL U1305, Equipe Labellisée Ligue Nationale contre le Cancer, 35000, Rennes, France.

BMC bioinformatics
|February 2, 2024
PubMed
概括

本研究介绍了Cirscan,这是一种工具,用于识别基因表达数据中的循环RNA (circRNA) 和microRNA (miRNA) 相互作用. 通过分析竞争性内源RNA (ceRNA) 网络,Cirscan帮助研究人员找到潜在的治疗点.

关键词:
癌症 癌症 癌症 癌症循环RNAs是一种循环RNA.规则 网络规则 网络规则一个海绵机制的机制.转录学数据 转录学数据

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...