美国成年人中的双S,双F,双A暴露和身体成分
Buyun Liu1, Yuxiang Yan1, Juan Xie1
1Institute of Public Health Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, China.
Chemosphere
|February 2, 2024
概括
双A (BPA) 和双S (BPS) 暴露与美国成年人体脂肪增加有关. BPA与较高的体脂相关,而BPS显示与体脂和瘦肉质相关.
科学领域:
- 环境健康 环境健康
- 内分泌学 在内分泌学.
- 人体生理学 人体生理学
背景情况:
- 双甲 (BPA) 是一种内分泌干扰的化学物质,具有潜在的肥胖效应.
- 双S (BPS) 和双F (BPF) 越来越多地被用作BPA的替代品.
- BPS和BPF对人类脂肪的影响需要进一步研究.
研究的目的:
- 为了检查尿液中的BPA,BPS和BPF度与美国成年人的身体组成之间的关联.
- 为了确定BPA的替代品 (BPS,BPF) 是否对身体脂肪和肌肉质量具有与BPA相似的影响.
主要方法:
- 在国家健康和营养检查调查 (2013-2016) 中分析了1787名美国成年人 (20-59岁) 的数据.
- 测量尿液中的BPA,BPS和BPF度.
- 使用双能X射线吸收计 (DXA) 评估身体成分.
- 使用调整的线性回归模型来评估关联的统计分析.
主要成果:
- 较高的BPA含量与全身,手臂和腿部的体脂%增加有显著的关联.
- 较高的BPS水平与增加的%体脂肪 (全身,干部,手臂) 和瘦肉量 (全身,干部,手臂,腿) 显著相关.
- 在BPF和身体成分参数之间没有发现显著的关联.
结论:
- 尿液中的BPA水平与美国成年人体脂肪百分比的增加有关.
- 尿液中的BPS水平显示出与增加的身体脂肪和瘦肉量都有潜在的关联,这表明存在复杂的关系.
- 需要进一步的研究才能充分了解BPS和BPF等BPA替代品对健康的长期影响.
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