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Updated: Jul 4, 2025

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
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Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

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在HSV-1和HSV-2感染期间,抗原呈现分子MR1的多目标损失

Carolyn Samer1, Hamish E G McWilliam2,3, Brian P McSharry1,4

  • 1Infection, Immunity and Inflammation, School of Medical Sciences, Faculty of Medicine and Health, and the Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia.

iScience
|February 2, 2024
PubMed
概括

简单疹病毒 (HSV) 感染减少了主要组织相容性复合体 (MHC) 与I类相关的 (MR1) 分子,该分子向MAIT细胞呈现微生物代谢物. 病毒蛋白破坏MR1的表达,在感染期间逃避免疫检测.

关键词:
细胞生物学 细胞生物学免疫学 免疫学 免疫学病毒学 病毒学

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