牙科检查和结直肠癌:台湾全国基于人口的嵌病例对照研究
Fu-Hsuan Liu1, Jing-Yang Huang2,3, Yu-Chao Chang1,4
1School of Dentistry, Chung Shan Medical University, Taichung, Taiwan.
Journal of dental sciences
|February 2, 2024
概括
被诊断为结肠直肠癌 (CRC) 的患者在诊断前更频繁地进行门诊牙科检查. 这表明口腔卫生保健使用与CRC风险之间存在潜在联系,需要进一步调查.
科学领域:
- 口腔健康研究研究 口腔健康研究
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 口腔健康与全身性疾病密切相关.
- 在结肠直肠癌 (CRC) 诊断之前,对牙科访问模式的了解有限.
研究的目的:
- 调查在台湾的门诊牙科诊所和CRC之间的联系.
- 澄清在CRC诊断之前的患者使用牙科护理的情况.
主要方法:
- 一个嵌套的病例控制研究,使用台湾的纵向健康保险研究数据库2010 (LHIRD 2010).
- 确定了4,787名CRC患者和19,148名对照人群,根据性别和年龄进行匹配.
- 追溯分析了指数日期 (CRC诊断) 之前8年内的门诊牙科访问.
主要成果:
- 与对照组相比,患有CRC的患者在诊断前的牙科访问的平均频率显著更高 (P=0.005).
- 在CRC患者中,某些并发症的患病率更高.
- 经过调整后,特定的牙科治疗 (牙周,牙损伤,拔牙) 并没有显著与CRC相关.
结论:
- 在后来被诊断为CRC的个体中,门诊牙科访问的利用率显著增加.
- 并发症可能会影响牙科诊所的频率和CRC的发生.
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