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Updated: Jul 14, 2026

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使用应用到基因表达数据的机器学习来高精度预测结直肠癌化疗的疗效

Soukaina Amniouel1, Mohsin Saleet Jafri1,2

  • 1School of Systems Biology, George Mason University, Fairfax, VA, United States.

Frontiers in physiology
|February 2, 2024
PubMed
概括

机器学习可以准确地预测哪些结直肠癌患者可以从FOLFOX或FOLFIRI化疗中受益. 这种方法可以识别那些可能对替代治疗有反应的患者,从而改善癌症护理.

关键词:
在FOLFIRII中,你会发现福尔福克斯 (FOLFOX) 是一个化学电阻是一种化学电阻.结肠直肠癌是什么意思功能选择 功能选择基因表达的基因表达方式机器学习是机器学习.

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...